Tag: genomic

Ionis and Genuity Science announce agreement designed to rapidly translate genomic insights into therapeutics

Genuity Science’s approach combines high-quality, whole-genome sequence and deep phenotype data resulting in better definition of the underlying disease mechanisms. This approach, when coupled with Ionis’ proprietary antisense technology, has the potential to significantly expedite the drug development process through a more direct translation of targets into therapeutics.

Under terms of the multi-year collaboration, Genuity Science will receive a combination of upfront payments and development milestones, plus product royalties.  

“Ionis’ financial strength and the success of our validated antisense technology have positioned us to invest in new technologies that enhance our R&D capabilities,” said Brett P. Monia, Ph.D., chief executive officer of Ionis. “The collaboration with Genuity Science gives us the potential to significantly increase our discovery opportunities and better understand the complexities of human diseases based on genetics.”

“We are excited to collaborate with an innovative company like Ionis,” said Rob Brainin, chief executive officer of Genuity

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Massive-scale genomic study reveals wheat diversity for crop improvement

Massive-scale genomic study reveals wheat diversity for crop improvement
Wheat grows at CIMMYT’s experimental station in El Batán, near Mexico City. A new study analyzing the diversity of almost 80,000 wheat accessions reveals consequences and opportunities of selection footprints. Credit: © Eleusis Llanderal/CIMMYT

Researchers working on the Seeds of Discovery (SeeD) initiative, which aims to facilitate the effective use of genetic diversity of maize and wheat, have genetically characterized 79,191 samples of wheat from the germplasm banks of the International Maize and Wheat Improvement Center (CIMMYT) and the International Center for Agricultural Research in the Dry Areas (ICARDA).


The findings of the study published today in Nature Communications are described as “a massive-scale genotyping and diversity analysis” of the two types of wheat grown globally—bread and pasta wheat—and of 27 known wild species.

Wheat is the most widely grown crop globally, with an annual production exceeding 600 million tons. Approximately 95% of the grain produced corresponds to bread wheat

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