Tag: chemically

FUJIFILM Irvine Scientific to Exclusively Distribute Chemically Defined Substrate for Stem Cell Culture

Cellnest substrate enables optimal adhesion and proliferation of stem cells for cell and gene therapy research

FUJIFILM Irvine Scientific, Inc., today announced that it has become the exclusive, worldwide distributor of cellnest®, a recombinant peptide attachment substrate that provides optimal adhesion and proliferation of stem cells in chemically defined, animal component-free conditions. Cellnest was designed and manufactured by FUJIFILM Corporation, joining its vast portfolio of solutions that support life science applications and therapeutic innovation.

Attachment substrates mimic the extracellular matrix (ECM), a complex and dynamic environment in which cells reside in vivo, in cell culture and allow for the adhesion, expansion, and potential differentiation of stem cells. Unlike animal-derived components, which can introduce unpredictability in results, the chemically defined, animal component-free formula of cellnest provides consistent results to researchers, and can smooth the regulatory path to commercialization. Cellnest is compatible with any adherent cell type that binds

Read More

Probing the origin of the mantle’s chemically distinct ‘scars’

Probing the origin of the mantle’s chemically distinct “scars”
Basalt, the most-common rock on Earth’s surface, encases green crystals–a geologic “nesting doll” phenomenon called a xenolith. Basalts such as this one derive from a section of the mantle that has been depleted in incompatible trace elements, which is usually attributed to continental crust formation. In their work, Tucker and his collaborators propose another mechanism that would impart this signature. Credit: Carnegie Institution for Science

The composition of Earth’s mantle was more shaped by interactions with the oceanic crust than previously thought, according to work from Carnegie’s Jonathan Tucker and Peter van Keken along with colleagues from Oxford that was recently published in Geochemistry, Geophysics, Geosystems.

During its evolution, our planet separated into distinct layers—core, mantle, and crust. Each has its own composition and the dynamic processes through which these layers interact with their neighbors can teach us about Earth’s geologic history.

Plate tectonic processes allow for continuous evolution of

Read More