Scientists to explore new frontiers in Parkinson’s disease research with $7.2M grant


IMAGE: This image depicts a model for how LRRK2 could block critical movement across the cell. The visualization shows a short LRRK2 filament (red, green and yellow) wrapped around a cellular…
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Credit: Leschziner Lab, UC San Diego

In August, a team of researchers at the University of California San Diego published groundbreaking back-to-back studies describing unprecedented details of a protein linked to genetically inherited Parkinson’s disease. The researchers produced the first visualizations of leucine-rich repeat kinase 2, or LRRK2, as seen within its natural environment inside the cell, as well as the first high-resolution blueprint of the protein.

The Aligning Science Across Parkinson’s (ASAP) initiative has announced support for the next phase of the research as the scientists focus on understanding the basic mechanisms underlying Parkinson’s, a neurodegenerative disorder affecting millions. ASAP’s goal is to support research that will inform a path to a cure for Parkinson’s. The

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